Study Identifies New Susceptability Loci for PTSD

We conducted genome-wide association analyses in 1578 European Americans (EAs), including 300 PTSD cases, and 2766 African Americans, including 444 PTSD cases, to find novel common risk alleles for PTSD. We used the Illumina Omni1-Quad microarray, which yielded approximately 870,000 single nucleotide polymorphisms (SNPs) suitable for analysis.

Co-Occurrence of Major Depressive Disorder Among Individuals With PTSD

This meta-analysis aimed to estimate the mean prevalence of current MDD co-occurrence among individuals with PTSD and examine potential moderating variables (U.S. nationality, gender, trauma type, military service, referral type) that may influence the rate of PTSD and MDD co-occurrence.

Mental health issues in recently returning women veterans

Community-based social workers need to be familiar with the needs of this growing population to serve them effectively. Use of empirically supported assessment instruments and screening for military sexual trauma are recommended.

Diffusion tensor imaging evidence of brain disruption associated with loss versus alteration of consciousness in combat veterans

The objective of this study was to examine the effects of LOC, MDD, and PTSD on white matter integrity in individuals who reported experiencing mTBI during combat in Operations Enduring and Iraqi Freedom.

Treatment of Comorbid Pain and PTSD in Returning Veterans

Objective We explore preliminary clinical effectiveness and feasibility of an intervention utilizing collaborative care components and behavioral activation (BA) to treat comorbid chronic pain and posttraumatic stress disorder (PTSD).

Mild Traumatic Brain Injury and Treatment Response in Prolonged Exposure for PTSD

Prolonged Exposure (PE) has proven effectiveness in the treatment of PTSD; however, some clinicians have reservations about using PE with individuals with a history of mTBI. We examined the impact of Prolonged Exposure (PE) for veterans with PTSD and with or without a history of mTBI in a naturalistic sample of 51 veterans who received PE at a Veterans Health Administration PTSD clinic.

Co-Occurrence of Major Depressive Disorder Among Individuals With PTSD

This meta-analysis aimed to estimate the mean prevalence of current MDD co-occurrence among individuals with PTSD and examine potential moderating variables (U.S. nationality, gender, trauma type, military service, referral type) that may influence the rate of PTSD and MDD co-occurrence.

Neurobiological insight into hyperbaric hyperoxia

Hyperbaric hyperoxia (HBO) is known to modulate aerobic metabolism, vasoreactivity and blood flow in the brain. Nevertheless, mechanisms underlying its therapeutic effects, especially in traumatic brain injury (TBI) and stroke patients, are debated. The present study aimed at investigating regional cerebral blood flow (rCBF) distribution during acute HBO exposure.

Role of growth hormone (gh) in the treatment on neural diseases

In this review we have analyzed the state of the art of GH administration in several neural diseases.

Role of Optical Coherence Tomography Raster Imaging as a Valuable Diagnostic Tool in the Differential Between Optic Disc Hemorrhage and Vitreopapillary Traction

This article highlights the use of spectral domain optical coherence tomography (SD-OCT) 5 line raster (5LR) in differentiating true optic disc hemorrhages from those as a result of tractional forces.

Qigong as a Novel Intervention for Service Members With Mild Traumatic Brain Injury

To describe the experience of internal qigong practice in service members diagnosed with mild traumatic brain injury (mTBI).

Posttraumatic Stress Disorder and Fear of Emotions

Anxiety is theorized to compromise attentional control. In turn, diminished attentional control may increase vulnerability to threat cues and emotional reactivity. Consequently, attentional control may play a role in the fear of emotions frequently experienced by individuals with PTSD.

Differential control of learning and anxiety along the dorsoventral axis of the dentate gyrus

The dentate gyrus (DG), in addition to its role in learning and memory, is increasingly implicated in the pathophysiology of anxiety disorders. Here, we show that, dependent on their position along the dorsoventral axis of the hippocampus, DG granule cells (GCs) control specific features of anxiety and contextual learning.

Influence of Trauma Exposure and Posttraumatic Stress Disorder Severity on Intimate Partner Aggression

The primary hypothesis was that PTSD would mediate the association between trauma exposure and intimate partner physical and psychological aggression with these effects evident both within and across members of a couple (i.e., actor and partner effects).

Repetitive Traumatic Brain Injury and Suicide - What is the connection?

This study investigated the association of cumulative TBIs with suicide risk in a clinical sample of deployed military personnel referred for a TBI evaluation.

Objective: To determine whether suicide risk is more frequent and heightened among military personnel with multiple lifetime TBIs than among those with no TBIs or a single TBI.